Daniel Attalla

Introduction Semax is a synthetic heptapeptide derived from the endogenous immunomodulatory peptide Tuftsin. Its sequence, Met-Glu-His-Phe-Pro-Gly-Pro, was engineered for enhanced stability, resistance to enzymatic degradation, and improved neuromodulatory properties. Research explores Semax’s potential influence on neurotransmitter regulation, stress-response signaling, BDNF-associated pathways, immune–neural communication, and cognitive processing networks. Structural Biology of Semax Semax...

Introduction NMN (nicotinamide mononucleotide) is a central intermediate in the NAD⁺ salvage pathway and is widely studied for its role in cellular metabolism, mitochondrial redox cycles, genomic maintenance, and energy signaling. As a precursor to NAD⁺, NMN significantly influences sirtuin activity, DNA repair processes, metabolic adaptation, and mitochondrial function. NAD⁺ Metabolism and the Salvage Pathway NMN is generated from nicotinamide via NAMPT, the rate‑limiting enzyme of the...

Introduction Selank is a synthetic heptapeptide derived from the endogenous immunomodulatory peptide Tuftsin. Its sequence, Thr-Lys-Pro-Arg-Pro-Gly-Pro, was engineered for enhanced stability, resistance to enzymatic degradation, and improved neuromodulatory properties. Research explores Selank’s potential influence on neurotransmitter regulation, stress-response signaling, BDNF-associated pathways, immune–neural communication, and cognitive processing networks. Structural Biology of Selank...