Disclaimer:
For research use only. Not for human consumption. Intended for laboratory-based studies by qualified professionals. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.
 
Overview:
Melanotan II is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH), studied for its ability to activate melanocortin receptors involved in pigmentation, energy regulation, and sexual function. It is a well-known research compound used to investigate melanin production, UV protection, and neuromodulatory pathways.
Mechanism of Action:
Melanotan II acts as a non-selective agonist of melanocortin receptors MC1R–MC5R, producing a broad range of biological effects. Activation of MC1R in melanocytes stimulates eumelanin synthesis, enhancing pigmentation and UV resistance. At the same time, MC3R and MC4R activation in the central nervous system has been linked to modulation of appetite, energy expenditure, and sexual arousal mechanisms.
Research Highlights:
Demonstrated stimulation of melanin synthesis and increased skin pigmentation in preclinical and clinical research.
Studied for potential protective effects against UV-induced DNA damage and oxidative stress.
Shown to influence hypothalamic pathways regulating energy balance and libido.
Serves as a model compound for studying melanocortin system activity in metabolic and neurological research.
Specifications:
Form: Lyophilized powder (research-grade)
Purity: ≥99% (HPLC-tested)
Storage: Store refrigerated (2–8 °C), away from light and humidity.